Book Cruises to South America

Featured South American Cruise Itineraries

South America is a land of natural wonders - Andes Mountains, Amazon rainforest, Patagonian glaciers, ancient Inca ruins, and Tierra del Fuego's dramatic seascapes. On an Oceania Cruises South America journey, the wild beauty of this continent is on brilliant display.

Witness the sprawling and spectacular wilderness of Patagonia, while indulging in the exquisite beef dishes and local Montevideo wines of Uruguay. Cruise through the snowcapped Chilean Fjords and visit with gauchos in Argentina. Venture high in the Andes Mountains to explore mysterious Machu Picchu, sail up the Amazon River into the mysteries of the jungle or soar above the Nazca Lines in Peru.

You will not only trek through rainforests and traverse deserts, but also delight in the nightlife in some of the world's most vibrant cities. Samba into the night in Rio or tango until dawn in Buenos Aires. The choice is yours.

On an Oceania cruise to South America, you'll visit exciting ports of call in Argentina, Brazil, Chile, Colombia, Ecuador, Peru, and Uruguay. Cruises depart from Rio de Janeiro or Buenos Aires; however, Oceania also offers departures from several North American cities including Miami, San Diego, and Vancouver.

South America Highlights

So many exotic and historic wonders exist within the scenic boundaries of this continent that you'll find it impossible to choose just one favorite moment from your South American journey!

Contact us to book your South America journey today.

CruisesShip Sort by ShipDate Sort by SaildateFare FromSavings
26-Nights from Miami to London Cruise Oceania SirenaMar 27, 2024$7,399$4,400
59-Nights from Miami to Rome Cruise Oceania SirenaMar 27, 2024$17,999$4,400
37-Nights from Miami to London Cruise Oceania SirenaMar 27, 2024$11,399$4,400
24-Nights from Cape Town to Lisbon Cruise  Oceania NauticaMay 21, 2024$9,799$4,860
10-Nights from Cartagena to Miami Cruise  Oceania NauticaDec 13, 2024$3,099$4,998
14-Nights from Miami to Bridgetown Cruise  Oceania SirenaDec 21, 2024$5,099$5,044
16-Nights from Los Angeles to Miami Cruise  Oceania VistaJan 24, 2025$7,399$5,136
18-Nights from Buenos Aires to Santiago Cruise  Oceania MarinaFeb 16, 2025$7,249$4,750
18-Nights from Santiago to Buenos Aires Cruise  Oceania MarinaMar 6, 2025$7,399$5,228
26-Nights from Cape Town to Barcelona Cruise  Oceania NauticaMay 22, 2025$10,699$5,596
20-Nights from San Diego to New York Cruise  Oceania InsigniaJul 3, 2025$5,699$5,320
34-Nights from Cape Town to Paris Cruise Oceania NauticaMay 21, 2024$13,299$4,400
36-Nights from Montreal to Miami Cruise Oceania NauticaOct 28, 2024$10,199$4,400
44-Nights Roundtrip from Miami Cruise Oceania NauticaNov 9, 2024$16,299$4,400
24-Nights Roundtrip from Miami Cruise Oceania NauticaNov 9, 2024$10,699$4,400
10-Nights from Miami to Cartagena Cruise Oceania NauticaDec 3, 2024$3,099$4,400
20-Nights Roundtrip from Miami Cruise Oceania NauticaDec 3, 2024$4,299$4,400
50-Nights from Miami to Rio de Janeiro Cruise Oceania MarinaDec 7, 2024$20,749$4,400
38-Nights from Miami to Buenos Aires Cruise Oceania MarinaDec 7, 2024$13,599$4,400
24-Nights from Lima/machu Picchu (callao) to Buenos Air... Oceania MarinaDec 21, 2024$8,249$4,400
36-Nights from Lima/machu Picchu (callao) to Rio de Jan... Oceania MarinaDec 21, 2024$10,899$4,400
32-Nights from Miami to Bridgetown Cruise Oceania SirenaDec 21, 2024$9,299$4,400
16-Nights from Miami to Los Angeles Cruise Oceania NauticaDec 23, 2024$4,749$4,400
18-Nights Roundtrip from Bridgetown Cruise Oceania SirenaJan 4, 2025$6,399$4,400
25-Nights Roundtrip from Bridgetown Cruise Oceania SirenaJan 4, 2025$8,199$4,400
196-Nights Roundtrip from Miami Cruise Oceania InsigniaJan 5, 2025$64,099$4,400
200-Nights from Miami to New York Cruise Oceania InsigniaJan 5, 2025$64,099$4,400
180-Nights from Miami to San Diego Cruise Oceania InsigniaJan 5, 2025$57,599$4,400
22-Nights from Miami to Rio de Janeiro Cruise Oceania InsigniaJan 5, 2025$9,649$4,400
44-Nights from Miami to Cape Town Cruise Oceania InsigniaJan 5, 2025$16,199$4,400
77-Nights from Miami to Singapore Cruise Oceania InsigniaJan 5, 2025$41,199$4,400
16-Nights from Miami to Los Angeles Cruise Oceania VistaJan 8, 2025$7,399$4,400
90-Nights Roundtrip from Miami Cruise Oceania VistaJan 8, 2025$37,499$4,400
12-Nights from Buenos Aires to Rio de Janeiro Cruise Oceania MarinaJan 14, 2025$5,499$4,400
21-Nights from Rio de Janeiro to Buenos Aires Cruise Oceania MarinaJan 26, 2025$7,899$4,400
22-Nights from Rio de Janeiro to Cape Town Cruise Oceania InsigniaJan 27, 2025$7,649$4,400
21-Nights Roundtrip from Miami Cruise Oceania SirenaFeb 8, 2025$6,499$4,400
18-Nights from Buenos Aires to Santiago Cruise Oceania MarinaFeb 16, 2025$46,999$4,400
11-Nights from Panama City to Miami Cruise Oceania SirenaFeb 18, 2025$4,299$4,400
111-Nights from Papeete to Barcelona Cruise Oceania NauticaFeb 25, 2025$40,899$4,400
10-Nights from Miami to Cartagena Cruise Oceania SirenaMar 1, 2025$4,099$4,400
22-Nights Roundtrip from Miami Cruise Oceania SirenaMar 1, 2025$6,599$4,400
63-Nights from Santiago to Barcelona Cruise Oceania MarinaMar 6, 2025$20,999$4,400
30-Nights from Santiago to Rio de Janeiro Cruise Oceania MarinaMar 6, 2025$11,599$4,400
12-Nights from Cartagena to Miami Cruise Oceania SirenaMar 11, 2025$4,599$4,400
20-Nights Roundtrip from Miami Cruise Oceania SirenaMar 23, 2025$5,899$4,400
12-Nights from Buenos Aires to Rio de Janeiro Cruise Oceania MarinaMar 24, 2025$5,599$4,400
38-Nights from Buenos Aires to Lisbon Cruise Oceania MarinaMar 24, 2025$13,599$4,400
45-Nights from Buenos Aires to Barcelona Cruise Oceania MarinaMar 24, 2025$16,499$4,400
10-Nights from Panama City to Miami Cruise Oceania SirenaApr 2, 2025$3,799$4,400
16-Nights from Rio de Janeiro to Santa Cruz De Tenerife... Oceania MarinaApr 5, 2025$4,749$4,400
26-Nights from Rio de Janeiro to Lisbon Cruise Oceania MarinaApr 5, 2025$7,399$4,400
33-Nights from Rio de Janeiro to Barcelona Cruise Oceania MarinaApr 5, 2025$9,499$4,400
61-Nights from Singapore to Barcelona Cruise Oceania NauticaApr 17, 2025$19,999$4,400
71-Nights from Singapore to Monte-Carlo Cruise Oceania NauticaApr 17, 2025$22,499$4,400
57-Nights from Auckland to New York Cruise Oceania InsigniaMay 28, 2025$16,699$4,400
37-Nights from Papeete to New York Cruise Oceania InsigniaJun 16, 2025$10,699$4,400
39-Nights from Rio de Janeiro to Santiago CruiseOceania MarinaJan 26, 2025$12,399
41-Nights from Boston to Miami CruiseOceania InsigniaOct 27, 2025$8,799
25-Nights Roundtrip from Miami CruiseOceania InsigniaNov 12, 2025$6,599
17-Nights from Miami to Los Angeles CruiseOceania VistaDec 3, 2025$6,699
197-Nights from Los Angeles to Miami CruiseOceania VistaDec 20, 2025$77,599
180-Nights Roundtrip from Miami CruiseOceania VistaJan 6, 2026$71,499
Fares are per person in US dollars, based on double occupancy. Savings, Onboard Credits and other amenity values are quoted per stateroom/suite. All prices, discounts and special offers are capacity controlled and subject to change without notice. Not all special offers available in all categories and sailings. Availability and pricing is not guaranteed until booking and deposit received.